£ 38.99
Zolpidem Tartrate 10mg Tablets contain zolpidem tartrate, a prescription sleeping medicine used for the short-term treatment of severe insomnia in adults when sleep problems are causing significant distress or affecting daily life. Zolpidem belongs to a group of hypnotic medicines commonly known as Z-drugs.
Zolpidem can help shorten the time it takes to fall asleep and reduce waking during the night. The 10mg strength is intended to be taken only according to the patient’s prescription and should not be repeated during the same night.
Because Zolpidem 10mg can affect memory, coordination and alertness, enough time should be allowed for uninterrupted sleep after taking it. Current product information recommends at least 8 hours before driving, operating machinery or carrying out activities that require full mental alertness.
For general information about sleep problems and non-medicine approaches, read our guide to insomnia, its causes and ways to improve sleep.
Zolpidem can cause tolerance, dependence, addiction and withdrawal reactions. It should therefore be used for the shortest appropriate period and exactly as prescribed.
Order by 1:30pm on a weekday to ensure your order is picked, processed and dispatched the same day, orders after 1:30pm will be dispatched on the next working day.
Please note:
Next-day Delivery UK orders between 1:30pm on Friday and 1:30pm on Monday are delivered on Tuesday.
Once we reach our cut-off point, which is 1:30pm, our team takes a short break from communications from 1:30pm until 5:00pm, so we can carefully pack and prepare our daily orders for next-day delivery. During this time, we may not be able to respond straight away, but we’ll pick up and reply to all messages as soon as we’re back at 5:00pm.
Royal Mail Delivery Charges:
Order on Monday - Thursday
Next-day Special Delivery (before 1pm): £10.50
Order on Friday
Next-day Saturday Special Delivery (before 1pm): £15.50
Bank holiday Mondays are a public holidays and therefore, Royal Mail do not operate a delivery service on these days, this also applies to all other public holidays such as Easter, Christmas Day, Boxing Day, New Years Day (1st).
If you order your parcel on a Bank Holiday weekend, it will be dispatched on Tuesday and delivery will take place on the Wednesday.
Zolpidem 10mg tablets are prescription sleeping tablets containing 10mg of zolpidem tartrate in each tablet.
Zolpidem is classified as a hypnotic or Z-drug. It acts within the central nervous system and is prescribed for the short-term management of insomnia in adults when the sleep problem is severe enough to cause significant distress or interfere with everyday functioning.
This medicine is also a Class C, Schedule 4 Part 1 controlled drug in the UK.
For other information relating to prescription medicines used in sleep disorders, visit the Sleeping Aids category.
Insomnia can involve:
Current UK Zolpidem product information states that underlying causes of insomnia should be considered wherever possible before hypnotic treatment is continued. If sleep problems persist, further medical assessment may be needed.
For more background on when this medicine may be used, see our Zolpidem Tartrate guide for insomnia.
Zolpidem influences the activity of gamma-aminobutyric acid (GABA), a chemical messenger involved in reducing activity within the brain and nervous system.
This sedative effect can make it easier to fall asleep and can reduce night-time waking. NHS guidance states that Zolpidem usually takes around 30 minutes to one hour to begin working, although individual response varies.
Do not take an additional tablet simply because you do not feel sleepy immediately.
Our UK guide to Zolpidem Tartrate provides broader educational information without turning this product page into a general Zolpidem encyclopaedia.
Zolpidem sleeping tablets are intended for short-term use.
NHS guidance says treatment is generally prescribed for 2 days to 4 weeks, while current UK product information states that treatment should be as short as possible and should not exceed four weeks, including any clinically appropriate reduction period.
Longer or repeated use increases the importance of monitoring for:
tolerance → dependence → addiction → withdrawal
The MHRA strengthened warnings for Z-drugs in January 2026 specifically around these risks.
For a broader comparison with other sleep medicines, see our Zolpidem Tartrate vs other sleep medications guide.
Take Zolpidem exactly as instructed on your prescription and dispensing label.
For adults, current product information identifies 10mg as the recommended daily dose, taken as a single dose immediately before bedtime. However, the lowest effective dose should be used and the total daily dose must not exceed 10mg. Some patients, including older adults and people with certain liver problems, may be prescribed a lower 5mg dose.
The 10mg shown on this product page describes the tablet strength and should not be treated as permission to select your own dose.
Swallow the tablet whole with water. It can be taken with or without food.
Zolpidem should be taken in one single intake and should not be taken again during the same night.
Do not:
If your sleep remains poor despite treatment, speak to the healthcare professional responsible for your care.
Plan for at least 8 hours between taking Zolpidem and activities requiring full alertness, such as driving or operating machinery.
This also helps reduce the risk of memory problems associated with Zolpidem.
If you forget to take Zolpidem at bedtime, skip the missed dose and continue the following night as prescribed.
Do not take two doses together and do not take an extra tablet to make up for a missed dose.
If Zolpidem has been used regularly, particularly for longer than the intended short treatment period, do not suddenly change or stop treatment without medical advice.
Current 2026 MHRA guidance warns that abrupt cessation or dose reduction can cause Zolpidem withdrawal symptoms. Where necessary, treatment may be reduced gradually according to an individual plan.
Like all medicines, Zolpidem can cause side effects, although not everyone experiences them.
Common Zolpidem side effects can include:
Speak to your doctor or pharmacist if side effects persist, worsen or interfere with your normal activities.
Zolpidem can occasionally cause memory loss or amnesia, particularly during the hours after taking it. Allowing around eight hours of uninterrupted sleep reduces this risk.
More unusual behaviours have also been reported while people were not fully awake, including:
Alcohol and other medicines that depress the central nervous system can increase this risk. If unusual sleep behaviour occurs, seek medical advice before taking further doses.
Zolpidem can cause tolerance, physical dependence and addiction.
Tolerance means the medicine may appear to work less effectively after repeated use. Do not increase the dose yourself if this happens.
Physical dependence means the body has adapted to Zolpidem and withdrawal symptoms may develop if regular treatment is suddenly stopped or reduced too quickly.
Possible Zolpidem withdrawal symptoms can include anxiety, restlessness, sweating, tremor, headaches, sleep disturbance, mood changes and rebound insomnia, where the original sleep problem temporarily returns more strongly.
Speak to your prescriber if you are worried about tolerance, dependence, addiction or stopping treatment.
Do not drink alcohol while taking Zolpidem.
Alcohol can increase sedation and may cause very deep sleep, impaired breathing and difficulty waking.
Tell your doctor or pharmacist if you take medicines including sedating antihistamines, antidepressants, medicines for anxiety or sleep, epilepsy medicines, antipsychotics or strong opioid painkillers.
Combining Zolpidem with opioids can increase the risk of severe sedation, respiratory depression, coma and death, so such combinations require particular medical caution.
Zolpidem can cause:
Current product information recommends allowing at least 8 hours after taking Zolpidem before driving, using machinery or working at height.
Do not drive if you remain sleepy, dizzy, clumsy or unable to concentrate safely.
Tell your healthcare professional before taking Zolpidem if you have conditions such as sleep apnoea, breathing problems, myasthenia gravis, liver or kidney problems, previous mental-health problems, or a history of alcohol or drug misuse.
Also seek individual medical advice if you are pregnant, planning pregnancy, or breastfeeding.
Taking more Zolpidem than prescribed can be dangerous, even if you initially feel well.
Symptoms after excessive Zolpidem can include:
If you take more than your prescribed dose, contact NHS 111 urgently for advice.
Call 999 or seek emergency care immediately if someone has severe breathing difficulty, becomes unconscious, cannot be woken, or develops a severe allergic reaction.
Do not drive yourself to A&E. Where possible, take the Zolpidem packaging, remaining tablets and information about other medicines being used.
Always read the patient information leaflet supplied with your actual Zolpidem Tartrate 10mg tablets before taking the medicine.
Current UK Zolpidem 10mg product information confirms that the medicine is a prescription-only film-coated tablet containing 10mg of zolpidem tartrate. The leaflet also includes strengthened warnings concerning dependence, tolerance, addiction and withdrawal.
The supplied leaflet should be checked for:
If the instructions on your dispensing label differ from general information on this page, follow the prescribed instructions and ask your doctor or pharmacist if anything is unclear.
Zolpidem is a prescription Z-drug sleeping medicine used for the short-term treatment of severe insomnia in adults. It can help people fall asleep more quickly and reduce waking during the night.
Zolpidem tartrate is the active medicinal ingredient contained in Zolpidem tablets. The product on this page contains 10mg of zolpidem tartrate per tablet.
NHS guidance states that Zolpidem usually takes around 30 minutes to one hour to begin working.
Do not take a second dose during the same night because the first dose does not appear to have worked immediately.
Yes. Zolpidem is a prescription sleeping tablet used for the short-term treatment of severe insomnia.
No. Zolpidem is not a benzodiazepine.
It belongs to a related group of hypnotic medicines known as Z-drugs, which act on the central nervous system to promote sleep.
Yes. Zolpidem is a Class C, Schedule 4 Part 1 controlled drug in the UK.
Yes. Zolpidem can cause addiction and physical dependence. It can also cause tolerance and withdrawal reactions. UK warnings for Z-drugs were strengthened in 2026 to communicate these risks more clearly.
If Zolpidem has been taken regularly, particularly for a longer period, do not stop suddenly without medical advice.
Abrupt discontinuation can cause withdrawal symptoms and rebound insomnia.
No. Alcohol should not be taken with Zolpidem because the combination can greatly increase sedation and may interfere with normal breathing or make it difficult to wake.
Yes. Sleepwalking and other behaviours while not fully awake have been reported with Zolpidem, including sleep-driving, preparing food and other activities that may not be remembered afterwards.
Both are prescription Z-drugs used for short-term insomnia, but they are different active medicines and have different pharmacological and dosing characteristics.
For the deeper comparison intent, use our Zolpidem vs other sleep medications guide rather than expanding this product page into a full comparison article.
See our Zolpidem Tartrate FAQ guide for additional general questions about the medicine.